Inositol is a naturally-occurring sugar alcohol or carbohydrate similar to glucose, and the body can convert glucose to inositol. There are multiple isomers or variants of inositol, one being inositol hexaphosphate. Inositol hexaphosphate is also referred to as ‘IP6,’ but is better known as phytic acid. Yes, this is the same phytic acid Paleo folks freak out about, but phytic acid is found in most mammalian cells and is often considered an essential nutrient, frequently being referred to as a vitamin informally [1].
Granted, large amounts of phytic acid can interfere with mineral absorption in the gut, so IP6 is simply a supplement you’d want to take away from food [2]. IP6 can be found naturally in many grains, nuts, seeds, legumes, fruits, and meats, for phytic acid is the major vehicle plants use for storing phosphorus [3]. The other two derivatives of inositol pertinent to our interests are myo-inositol and D-chiro-inositol. IP6, myo-inositol, and D-chiro-inositol are all structurally related, but have different effects in the body, so I will refer to them separately. Now, PCOS (polycystic ovarian syndrome) is a condition of hormonal imbalance typically involving a constellation of such symptoms as irregular menstruation, anovulation (ovaries not releasing eggs), high androgen levels, and the presence of cysts in the ovaries. Inositol derivatives have been shown to possess significant potential for the natural treatment of PCOS. What does the medical literature say? Firstly, the safety of myo-inositol, D-chiro-inositol, and inositol hexaphosphate supplementation has been clearly demonstrated, with side effects such as mild nausea and flatulence only occurring with inappropriately high doses [4] [5] [6]. The metabolism of inositol is usually on the fritz within PCOS ovaries, which impairs the action of insulin and the production of steroid hormones like progesterone. Administering myo-inositol can improve insulin sensitivity (even specifically at the ovaries) as well as counter high androgen levels and infrequent menstruation (partly by changing the cytoskeletal architecture of ovarian follicles) [7] [8]. Myo-inositol significantly outperformed metformin (a pharmaceutical commonly prescribed for PCOS which blocks glucose release by the liver) in decreasing serum testosterone, downregulating expression of the proinflammatory cytokine interleukin-1, and lowering C-reactive protein levels (a marker of inflammation) [9]. Combining myo-inositol with D-chiro-inositol has proven to be even more effective for PCOS, regularizing the menstrual cycle and dropping cardiovascular disease risk by improving dyslipidemia [10] [11]. Myo-inositol and D-chiro-inositol can act as insulin mimetics and therefore lower post-prandial (after eating) blood sugar levels (insulin resistance is a chief factor in the etiology of PCOS) [12] [13]. As a side note, both myo-inositol and D-chiro-inositol can help protect against neural tube defects (like spina bifida) [14]. D-chiro-inositol by itself is quite effective in bettering insulin sensitivity, lowering blood pressure and plasma triglyceride concentrations, dropping serum testosterone, and reestablishing ovulation [15]. PCOS has been associated with a higher risk of ovarian and endometrial cancers, but fret not my friends, for inositol hexaphosphate (IP6) can directly inhibit cancer cell growth and prevent tumorigenesis in the first place [16]. IP6 has clearly showcased its efficacy as an anticancer agent via its ability to induce the differentiation of cancer cells (stopping the assumption of stem cell-like states where cells multiply rapidly), arrest abnormal cell proliferation, prevent tumor formation, trigger apoptosis (cell death signaling) in cancer cells, serve as an antioxidant, bolster the immune system, thwart cancer cell angiogenesis (the formation of blood vessels to feed cancer cells), and downregulate the expression of genes related to proinflammation [17] [18] [19] [20] [21] [22]. Combining IP6 with inositol is even more effective in treating cancer, and both can be used safely alongside chemotherapy (not that I’m condoning the use of chemotherapy, I’m just saying) [23]. Myo-inositol and D-chiro-inositol also share some anticancer potential with IP6 [24] [25]. So inositol derivatives can impressively treat and help correct both PCOS and cancer, as well as aid in the thwarting of these conditions’ manifestation in the first place. And all of these derivatives are safe and compatible with the body, as they’re found normally in the diet. Once again, in natural medicine we find answers. Have an excellent weekend. References:
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A migraine can be described as an attack of severe pulsing or throbbing pain in the head region, usually more on one side [1]. Nausea, vomiting, lightheadedness, fatigue, and intense sensitivity to light and sound often accompany the pain [2]. The characterizing pain can last for hours or fluctuate for days, and can easily be disabling. And the term migraine can be seen as an umbrella under which different types like basilar artery migraine, retinal migraine, and hemiplegic migraine exist.
Indications of an oncoming migraine can include tingling in the face, the appearance of one or more blind spots in the field of vision, perceived flashes of light, or other visual disturbances [3]. Other symptoms such as muscle weakness, difficulty with speech, hot or cold sensations, or involuntary movement may also be seen at some point. A progression through four stages often occurs when a migraine is experienced, and these four stages are labeled prodrome, aura, headache, and postdrome. During the postdrome phase, most experience hangover-like symptoms such as tiredness and a low-grade headache, though some report feeling refreshed and almost euphoric [4]. Some kind of irregularity in the brain’s vascular system, being either a structural or perfusion issue, is commonly associated with the pathology of migraines [5]. Though evidence exists for possible genetic predispositions as well [6]. An MRI, CT scan, spinal tap or lumbar puncture (collecting of cerebrospinal fluid sample), or some manner of a blood test may be used in determining potential causes for recurring headaches or migraines. The current prevailing theory suggests that migraines manifest as a result of cranial nociceptors (pain sensors), which innervate blood vessels in the meninges, being activated and abnormally sensitized, and then creating prolonged pain each time their sensitization is triggered by one or more stimuli [7]. When the meninges are chemically irritated, their housed nociceptors can become sensitized for a fair amount of time, and this sensitization conjures the throbbing pain of a migraine (which is aggravated by anything that increases pressure in the cranium), for without sensitization meningeal nociceptors either respond minimally or not at all to mechanical stimuli. Once the sensitization period ends, the nociceptors cease being so touchy, and the migraine pain fades. So what can be responsible for irritating the meninges? Good question. A transient drop in serotonin has been proposed as one factor which activates the trigeminovascular system (a collection of neurons in the fifth cranial nerve) and leads to a release of neuropeptides (like substance P and calcitonin gene-related peptide) from the meninges that transmit signals of throbbing pain [8]. And inflammatory mediators such as bradykinin, histamine, and prostaglandin E2 have also been identified as potential culprits in the sensitization of the trigeminovascular system [9]. These inflammatory mediators are released in response to nervous tissue injury or a buildup of things like hydrogen ions and glutamate within the brain, which means that neurogenic inflammation can be created by irritants (e.g., toxins, food protein antigens, lipopolysaccharide, heavy metals, etc.) breaching the blood-brain barrier and invoking brain tissue injury [10]. A leaky blood-brain barrier then, should be a common finding in those who suffer from recurrent migraines, and indeed proinflammatory cytokines (which can be quite rampant in GI conditions like inflammatory bowel disease) have been found in the serum of migraineurs during migraine attacks [11] [12]. And these cytokines can sensitize the same nociceptors in the meninges discussed above [13]. Because a leaky brain is reflective of a leaky gut, migraines may be much more of a gastrointestinal issue than a cerebral one [14] [15]. In one study involving the use of four probiotic strains and a blend of herbs and nutrients designed to assist the liver and kidneys, 60% of the subjects reported experiencing almost total relief from migraine attacks, indicating how important a clean colon and intact gut wall can be for the correction of migraine suffering [16]. Now let’s list some specific factors that can contribute to the onset of migraines: - Estrogen dominance or abnormal estrogen fluctuations (usually a significant drop in estrogen around the time of menstruation) [17]. - Aspartame and monosodium glutamate [18] [19]. - Alcohol [20]. - Caffeine [21]. - Jet lag or a disrupted circadian rhythm [22]. - Excessive physical exertion [23]. - Vitamin B2 or magnesium deficiency [24] [25]. - Low concentrations of vitamin D or CoQ10 (or metabolic abnormalities involving these nutrients) [26] [27]. - Hypoglycemia or insulin resistance [28] [29] [30]. - Psychological stress (relatedly, some studies have noted that childhood traumas like physical or sexual abuse are more frequent in migraineurs) [31]. - Eye strain or excessive blue light exposure from computer or cell phone screens [32]. - Obstructive sleep apnea as well as teeth grinding or TMJD (temporomandibular joint dysfunction) [33] [34]. - Dehydration [35]. - SIBO (small intestinal bacterial overgrowth) or SIFO (small intestinal fungal overgrowth, a.k.a. intestinal candidiasis) [36]. - Environmental allergens (from things like dust and mold) and food allergens (from foods like wheat and conventional cow’s milk) are common migraine triggers [37] [38] [39]. Now let’s cover some natural treatment options: - CoQ10, L-carnitine, and alpha-lipoic acid can reduce the frequency and severity of migraines, for recurrent migraines have been linked to mitochondrial dysfunction [40] [41] [42] [43]. - Lavender, eucalyptus, chamomile, and rosemary essential oils can be of some use in the acute treatment of migraines [44] [45]. - Acupuncture can be safely administered for just about any condition, and its efficacy in treating migraines has been demonstrated [46] [47]. - Yoga therapy has proved to be worth mentioning in the reduction of psychological tension for migraine sufferers [48]. - Vitamins B6, B9 (folate), and B12, with the intent of lowering homocysteine levels, can be effective aids [49]. - Because endocannabinoids can inhibit nociceptive signaling from the trigeminovascular system, CBD oil may be of some use in treating migraines, at least palliatively [50] [51]. - One study administered a supplementation protocol consisting of zinc sulfate and vitamin B-complex for six weeks (plus either vitamin A or vitamin E for the first ten days) to 30 migraineurs, and reported an almost complete disappearance of migraine attacks in all 30 subjects [52]. - The herbs feverfew and butterbur have been shown to help prevent and reduce the severity of migraines [53] [54] [55]. - Ginger has also been used safely and successfully in the treatment of migraines, and fish oil has exhibited some potential as well [56] [57] [58]. - DIM or diindolylmethane may be helpful for menstrual migraines as it can improve estrogen metabolism and the excretion of synthetic estrogens [59]. - Gastrodin, a polyphenol extracted from the herb gastrodia elata, can better cerebral blood flow and lower the concentration of excitatory neurotransmitters in the brain (specifically it can inhibit trigeminal nerve activation), which is why it has been found to be quite therapeutic in reducing the frequency and severity of migraine attacks [60] [61]. In conclusion, I feel that the resolving of most migraine etiologies lies in the correction of intestinal dysbiosis and a leaky gut, detoxifying the brain, reestablishing the integrity of the blood-brain barrier, and then repairing damaged hormone receptors (note that insulin’s receptor is located within plasma membranes, so the repairing of plasma membranes may need to be a therapeutic target too). Once these steps are completed, the fixing of simple nutrient deficiencies (often vitamin D, magnesium, and vitamin B2 in migraineurs) can be easily achieved. References:
Fecal microbiota transplantation (FMT) is a therapy performed either on one’s own or with the assistance of a physician that involves introducing an infusion of human stool from a healthy donor into the subject’s colon through the rectum via direct implantation (using a colonoscope or retention enema) or through the mouth via freeze-dried capsules (much like the taking of a regular probiotic supplement) [1].
Administration via a nasogastric, nasoduodenal, or nasojejunal tube is less common (note that with a colonoscope, the entire colon can be inoculated). FMT is administered for the purpose of fostering the reestablishment of eubiosis or a healthy population of microorganisms in the gastrointestinal tract [2]. Other terms such as stool transplant, fecal transplant, fecal transfusion, fecal bacteriotherapy, and human probiotic infusion may be used to refer to fecal microbiota transplantation, but these terms have largely been replaced by FMT (at least in the research literature) [3]. FMT has been used with remarkable success in the treatment of Clostridium difficile infections, but studies from around the world are highlighting that its clinical application is much more extensive [4]. To my knowledge, FMT was first employed to treat pseudomembranous colitis (which can result from a C. diff infection) in 1958, though the utilization of human fecal material as a medicament likely originated with the physicians of ancient China [5] [6]. Donor selection, preparation of the infusion, and preparation of the patient are aspects that can vary in FMT, but the safety of FMT has been clearly demonstrated (as long as the donor is truly healthy and the procedure is performed correctly), and geriatric, pediatric, and immunocompromised patients being treated for Clostridium difficile infection have all safely received FMT [7] [8] [9]. If side effects are reported, they’re usually transient and mild (temporary diarrhea, constipation, or abdominal cramping have been seen) [10]. For individuals with inflammatory bowel disease (ulcerative colitis or Crohn’s disease), FMT has exhibited substantial efficacy, with many seeing clinical remission (though not everyone experiences the same results) [11] [12] [13]. And FMT has proved to be significantly effective for those with metabolic syndrome, irritable bowel syndrome, chronic fatigue syndrome, and multiple sclerosis (though again, not everyone sees the same benefit) [14] [15] [16] [17]. FMT has also been found to be beneficial for Parkinson’s disease, alopecia, and autism [18] [19] [20]. Because of the immense roles played by GI microbes in the body’s immune, inflammatory, and metabolic activities, FMT is being looked at as a potential means for improving transplantation outcomes in organ transplant recipients [21]. Irrefutable is the criticality of the microbiome’s intimate relationship with the food we eat, the environment we’re exposed to, and even the thoughts and emotions we subject the enteric nervous system to in the establishment of physical wellness [22]. Restoring a healthy diversity to the intestinal microbiota by way of FMT can be much more helpful for some than simple probiotic supplementation, since human feces houses an elaborate microbial community combined with other constituents like vitamins and proteins [23]. Stool infusions can be crafted using water, sterile saline, milk, or saline with psyllium as the diluent [24]. The final solution may be filtered through a strainer or gauze pad (or pureed with a blender) to thin and partially homogenize the mixture [25]. Donor stool can be employed fresh within eight hours of passage, or a frozen sample can be used. And multiple implantations or administrations may be required to adequately treat whatever condition the patient is dealing with. So, FMT presently stands as a therapeutic modality with notable potential, but it is certainly not completely free of risk or possible detriment. In the future, I believe its application will grow in scope and sophistication, but for now, its clinical access is limited [26]. Currently in the United States, FMT can only be administered by a physician for the treatment of C. diff infection (thanks to the FDA’s ruling in 2013 which classified human fecal matter as both an investigational new drug and a biological medical product) [27]. Hopefully the FDA’s stance will change in the near future. Outside of the U.S., multiple clinics exist which offer full-service FMT for issues other than C. diff infection. Although, a U.S.-based physician can assist with donor screening and advise their patient as to how to perform FMT at home. For those interested, much more information on FMT (including do-it-yourself instructions and advice) can be found at https://thepowerofpoop.com/. References:
Endometriosis can be defined as a condition involving tissue from the endometrium (the inner lining of the uterus) being displaced and implanted in other areas of the body, such as the ovaries, fallopian tubes, vaginal canal, bladder, or colon [1]. Adenomyosis is a similar condition in which endometrial tissue penetrates into the muscular layer of the uterus (the myometrium). Displaced endometrial tissue can also be deposited outside of the pelvic region if transported by the blood or lymph [2].
Some common symptoms of endometriosis include pelvic pain, heavy bleeding during menstruation, bleeding in-between periods, infertility or subfertility, pain with intercourse, pain with urination or defecation, low-back pain, significant dysmenorrhea or menstrual cramps, and bloating or nausea during periods [3]. Though some women with endometriosis are asymptomatic. Endometriotic lesions can generate soft tissue adhesions that bind internal organs together, interfering with the blood supply, waste expulsion, or normal function of the organs affected (issues with the ovaries are commonly due to such adhesions) [4]. And it’s worth noting that endometrial implants can form their own nerve and blood vessel supplies [5] [6]. Diagnosing endometriosis may be done via manual pelvic exam, transvaginal or abdominal ultrasound, or laparoscopy (errant endometrial tissue can also be removed through a laparoscopy). Genetic, epigenetic, and environmental factors can all be at play in the pathogenesis of endometriosis, and oxidative stress, inflammatory cytokines, and hormonal aberrations are classical ingredients [7]. Retrograde menstruation (menstrual debris flows back into the fallopian tubes and then into the peritoneal cavity) may be involved in some cases of endometriosis, but Hufnagel et al. argue that altered stem cell trafficking characterizes endometriosis since it has been found that both endometrium-derived and bone marrow-derived stem cells can migrate throughout the body and contribute to the onset of this condition [8] [9]. The endometrium is comprised of a basal layer and a functional layer, the functional layer (termed the stratum functionalis) is normally shed during menstruation, while the basal layer (termed the stratum basalis) normally remains intact. The basal layer houses stem cells which regenerate the functional layer as needed [10]. It has been observed that women with endometriosis shed fragments of the endometrium’s basal layer with a higher prevalence than women without endometriosis [11]. And both endometrium-derived stem cells and mesenchymal stem cells can migrate to ectopic sites in the body and differentiate into endometrial tissue [12]. Well known is the fact that progesterone receptor-resistance and estrogen dominance or excessive estrogen signaling have been associated with endometriosis [13] [14]. Hormone receptors can be easily damaged by toxins and free radicals (leading to hormone receptor resistance), but we’ll talk more on what to do about this later on. Findings have suggested that the metabolism of retinoic acid (a metabolite of vitamin A) is flawed in those with endometriosis, and inadequate retinoic acid levels could impair the scavenging function of macrophages (which normally gobble up endometrial cells that find their way out of the uterus), permitting the colonization of endometrial tissue at ectopic sites [15]. Indeed, retinoic acid administration (in murine models) inhibited the colonization of endometrial tissue and significantly reduced the size of existing endometrial implants [16] [17]. This indicates that reasonable vitamin A supplementation may be helpful for women with endometriosis. Also note that many other things can be responsible for the defective immunosurveillance that facilitates the development of endometriosis. The misexpression of multiple microRNAs has been seen in endometriosis, but DNA damage from toxins and free radicals is likely to blame for this [18] [19]. Dioxins, phthalates, polychlorinated biphenyls (PCBs), and other toxins have been strongly linked to endometriosis [20] [21] [22] [23]. It has also been hypothesized that Shigella bacteria or Shigella-like microorganisms might be the trigger for at least some cases of endometriosis [24]. Shigella bacteria usually gain access to the body through the mouth. Arguments have been made for endometriosis at least sharing some characteristics with autoimmune conditions, such as elevated cytokines, thwarted apoptosis (programmed cell death), the presence of autoantibodies, and abnormalities in the cell-mediated arm of the adaptive immune system, but the survival of ectopic endometrial engraftments depends on a kind of relaxing of the immune response, rather than a confusion or overactivity of it [25] [26]. It seems that estrogen receptor beta is a major player in establishing a conducive immune environment for endometrial growths to set up shop [27]. Certainly endometriosis can be a complex and multifactorial ailment, so a comprehensive and individualized program may be very necessary for its complete resolution. But here are some tips and natural treatment options that could be helpful. The conventional approach of simply prescribing NSAIDs and hormonal contraceptives will just make things worse in the long run. Multiple herbs and herbal formulas from the toolbox of Traditional Chinese Medicine have long been significantly effective for the treatment of endometriosis [28] [29]. Specifically, Chinese angelica, corydalis, turmeric, and red peony root (among multiple others) have been used with success [30]. EGCG (epigallocatechin gallate) from green tea and resveratrol from red grapes have been seen to inhibit the development of endometriotic lesions and reduce the size of existing lesions through reactivating apoptosis, blocking cell proliferation, and retarding angiogenesis (the making of blood vessels to feed ectopic endometrium) [31]. EGCG and resveratrol can both be acquired in isolated supplement form. Because of its high vitamin A, vitamin D, and omega-3 fatty acid content, cod liver oil could be a useful supplement for those with endometriosis [32]. Because of vitamin D’s role as an immunomodulatory and anti-inflammatory agent, its deficiency has been associated with the pathogenesis of endometriosis [33]. A gemmotherapeutic extract of Rubus idaeus (European raspberry) can work well for dysmenorrhea, uterine spasms, pelvic pain, and female hormone irregularities, as well as for draining the uterus and pelvic region, and therefore could be beneficial for endometriosis [34]. Acupuncture can be employed to treat pelvic pain but more importantly it can help to relieve congestion [35]. Castor oil can be applied topically to the abdominal or pelvic regions for its analgesic and anti-inflammatory effects, but castor oil can also serve as a detoxification and immunomodulation aide [36]. In one study, 47 subjects with endometriosis were given 600 mg of N-acetylcysteine three times per day, on three consecutive days each week during a period of three months [37]. 24 of these subjects decided to cancel their scheduled laparoscopy because of a decrease or complete disappearance of endometriomas (a type of ovarian cyst), significant pain reduction, or pregnancy (again, many with endometriosis experience infertility or subfertility). We know that prostaglandin E2 is a powerful stimulator of aromatase (a key enzyme that makes estrogen), and N-acetylcysteine can block the enzyme COX-2, which can lower prostaglandin E2 output and reduce the availability of estrogen to ectopic endometrium [38]. In other words, N-acetylcysteine can help turn off the estrogen fuel supply of endometrial growths safely and without side effects. Now let’s take a step back and look at the bigger picture in our designing of a treatment program. Firstly, here are some questions we might need to ask ourselves. Does the patient have any food allergies or sensitivities? How are their adrenals doing (cortisol and DHEA can be easily measured)? What’s their current estrogen and estrogen metabolite status (also easily measured)? Are they able to efficiently clear estrogen from the body (is their liver hampered and are they methlyating well)? Is their gut motility normal or are they constipated? How’s their diet? Are they taking in enough B vitamins, magnesium, and fibrous vegetables [39]? Are they currently consuming gluten? Because a gluten-free diet alone can significantly reduce pelvic pain in at least some with endometriosis [40]. And don’t forget emotional and psychological stressors, as wisely stated by Dr. Joel Evans, “I have witnessed in my own clinical practice the direct impact that emotional and spiritual issues – such as childbearing conflicts, lack of creative self-expression, sexual issues, unresolved anger, and severe self-criticism – have on these illnesses [speaking to fibroids, endometriosis, and breast cancer] in my patients” [41]. Moving on, estrogen metabolism should be a major focus in the correction of endometriosis, so let’s look at that now. Estrogen is biotransformed in the liver and then enters the small intestine by way of bile to ultimately be excreted via stool. So estrogen clearance can be obstructed if the liver’s detox pathways are hindered, or the gut is congested or overly static. Exercise, flaxseeds, and indole-3-carbinol (can be obtained through cruciferous vegetables or an isolated supplement) can help the liver’s phase 1 detox pathway hydroxylate estrogen [42] [43]. Glucuronidation during phase 2 in the liver can be augmented by supplementing with calcium-D-glucarate, which will help ensure that processed estrogen is converted into a water-soluble form so that it can be eliminated from the body [44]. Calcium-D-glucarate can also inhibit beta-glucuronidase, an enzyme produced by gut bacteria that can cleave off the glucuronic acid fragment of estrogen conjugates and allow for active estrogen to be reabsorbed via enterohepatic recirculation or the flow of things from the liver to the gut and then back to the liver [45]. A high concentration of beta-glucuronidase is usually the result of gut dysbiosis. Next, blood sugar regulation is important for endometriosis patients, because insulin stimulates the aromatase enzyme (which synthesizes estrogen) and insulin lowers sex hormone-binding globulin (a protein that carries estrogen in the blood). So the more insulin that is produced each day, the more estrogen that will be available to endometrial tissue. Also, appropriate weight loss can be beneficial for those with endometriosis, because adipose tissue contains aromatase and thus manufactures estrogen, and when fat cells become overfilled they can drive up insulin levels as they release less of the hormone adiponectin [46]. And with more insulin comes more estrogen. If that wasn’t enough, fat cells also secrete proinflammatory cytokines that stimulate aromatase too, so the more fat you’re carrying, the more estrogen you’ll be making. Cinnamon, chromium, vanadium, and alpha-lipoic acid can all improve blood glucose regulation when used alongside a healthy diet [47] [48]. Bromelain (a proteolytic enzyme), quercetin (a flavonoid), and curcumin (an extract of turmeric) are additional great options for anti-inflammatories [49] [50]. Lastly, reducing exposure to environmental estrogens by consuming organic food, being careful with plastics, and filtering your water can be very important for lowering the body’s estrogenic load. I hope this article provided you with some optimism as endometriosis is definitely resolvable with natural medicine, though it can take some time. And if you’re a healthcare provider who works with folks that have endometriosis, hopefully this article offered some useful guidance. References:
Trying to keep this discussion short and sweet, let’s first quickly say a few words about time.
The Wheeler-DeWitt equation seeks to marry the worlds of quantum mechanics and general relativity while arguing that time is not really an acting variable, but is instead “laid out” much like the dimension space is conventionally described as being laid out [1]. This model allows for a timeless universe in which the past, present, and future exist simultaneously and are equally accessible. From a spiritual stance, we know this to be the case in that there is only an eternal present, which invalidates the theory that the universe was created by a giant and coincidental explosion a while back. Our perception of the movement of time is due largely to the lower mind’s linear sequencing of events. Now let’s look at the “adhering” of traumatic residues to the physical body and its operation. Cytoskeleton and glycocalyx (a carbohydrate meshwork that projects out of and covers cell membranes) components make up part of what is collectively referred to as the ‘living matrix,’ and these components function as both receivers and emitters of quantum information that resonate with particular frequencies [2]. These components of cells also play a liaison role in that they interface with both endogenous (internally produced) and exogenous (externally produced) electromagnetic fields [3]. Because thoughts and emotions can operate within the spectrum of electromagnetic wavelengths, they can be liaised by cellular receptors, as well as “stored” within the crystalline apparatuses of the body, including intracellular water. Structured water (or water’s fourth phase) inside cells not only serves as a battery but also a medium for the transferring of information encoded within electromagnetic fields generated by the body and directed to the body from outside [4]. Cellular proteins and DNA respond to the data relayed by both structured water and the living matrix components discussed above, and coherent water’s incredible office of facilitating self-organization in single cells at the micro level and in ecosystems at large at the macro level has been explored at length [5]. Joachim Keppler has suggested that the brain is capable of extracting and filtering information from the zero-point field, and that as the brain assumes different brain wave states (gamma, theta, beta, etc.), a different level of processing and integration of the entertained data takes place [6]. In this model, the zero-point field provides the background activity or “noise” of the brain. To offer an analogy, in the middle of a basketball game, an NBA player can filter out and respond to the voice of a teammate, while ignoring the background noise of the crowd. Furthermore, additional stimuli from the player’s coach, a referee, and a second teammate can be filtered out from the background noise of the crowd and layered into a “cake” of information that can be processed collectively and simultaneously. Essentially, the brain does the same thing with data from the zero-point field. Coming back to structured water, interfacial water also interacts with the zero-point field and promotes the extension of ‘coherence domains,’ which I have contended supports the removal of inharmonious signatures or imprints (like thoughts and emotions associated with trauma), and the adoption of harmonious ones (like safety, peace, and love) [7]. Therefore, the greater the amount of structured water residing in your body, the more amenable your body should be to the removal or resolution of psychological or emotional trauma (if you’re interested, I have a presentation on structured water that is a constituent of my certification course). One more thing, the “slate” of the beliefs and memories instilled within the body’s water can be quite easily “wiped clean” by the New Energies upon transitioning to a breatharian or pranic living state, but the same releasing can also be achieved simply through intent and trust in the I AM, as all roads lead to Rome as we progress further into Aquarius. In conclusion, consciousness irrefutably represents the “most basic building block of nature and consequently is present at all levels of the fabric of reality” (as offered by Meijer and Geesink) [8]. Our holographic, mental workspace mediates the attaining of cortical (referring to the cerebral cortex) resonance patterns that guide the ever-evolving integration of the self. Accordingly, our spiritual growth is a beautiful process that is always tinged by the love that pervades the universe. Now, more than ever, it is time for us to open ourselves to this love and embrace the divinity that is our immutable core. References:
In this short article, I would simply like to offer a few points in order to equip you with a better understanding of the human immune system so that you can make more informed decisions concerning vaccines.
From the outset, there can be no argument to the statement that vaccination does not confer true and lasting immunity from a particular disease state, despite vaccinology’s central pillar. The human body and its microbial environment have coevolved along Nature’s guiding hand for far longer than typically appreciated, and our immune systems have not been designed with any defect or incompetency. It is only when we sabotage the immune system’s inherent robustness with toxins, pharmaceuticals, improper nutrition, and vaccines that immune weaknesses are forced into manifestation. Looking at viruses specifically, the human virome houses trillions of viruses, and these viruses are essential to the proper ontogeny of the supraorganism that is the human body [1]. Assuming that all viruses are pathogenic parasites is a great example of the Pasteurian idiocy that blights the ivory towers of allopathic medical schools. Viruses serve as a major component of the internet that connects organisms within an ecosystem together for the maintaining of harmony and the coevolution of involved genomes. Granted I’m referring to natural, wild viruses and not the machines of genetic corruption fabricated by the servants of Illuminatus agendas. Now, wild exposure to viral pathogens during childhood naturally tutors and strengthens the cell-mediated arm of the adaptive immune system, while directly injected vaccines are aimed at the forced production of antibodies from the humoral arm of the adaptive immune system. Early vaccinations then, can create a weakening of cell-mediated immunity and a hypervigilance of humoral immunity [2]. Human infants should be protected against viral invaders while their immune system is still maturing through the transferring of antibodies via the mother’s placenta and breastmilk, when the mother has established true immunity against such invaders by way of wild exposure. Vaccinated mothers do not transfer the same level of antibody protection to their breastfeeding newborns, leaving such infants more susceptible to viral infection. In a way, a breastfeeding infant remains an extension of its mother in that breastmilk guides immune programming in the infant, supplies stem cells with multilineage potential, delivers HAMLET (a combination of alpha-lactalbumin and oleic acid) which patrols the infant’s body and arrests abnormally proliferating cells (to thwart cancer), and offers beneficial bacteria for the further establishment of the neonate’s microbiota [3] [4]. Neonatal CD71+ cells help protect against aberrant intestinal inflammation or intestinal immune cell activation as the gut is rapidly colonized with commensal microbes in the early stages of life outside the womb [5]. This checking of immune cell activation prevents the onset of chaos while the infant’s immune system is being tutored by natural exposure to microbes and potential antigens, as the immune system and microbiota develop in tandem. However, early antibiotic use can severely interfere with the microbiota’s development and thus the immune system’s normal education (remember that some vaccines contain antibiotics). Furthermore, the so-called “non-inflammatory phenotype” is expressed in a developing infant as the default program to permit events of tissue growth and remodeling, while the immune system learns essentially what to respond to and what not to respond to [6]. Allergic and inflammatory dispositions are avoided when this schooling is carried out correctly, while the same are promoted when immune responses are forced through the onslaught that is the CDC’s current vaccination schedule [7]. Once a child has been weaned off of breastmilk, their immune system should be ready to appropriately handle wild virus exposure, and then conjure true and lasting immunity to encountered viral pathogens. This is the template Nature has designed for the human body’s construction of viral immunity, and this process cannot be mirrored through the use of vaccinations. Viral diseases should only be potentially lethal in infants who are not being shielded by maternal immunity and in those who are severely immunocompromised or malnourished. In both populations, wild viruses are not to blame, but instead administered vaccines, toxins, nutrient deficiencies, and other stressors are foiling the immune system’s normal functionality. It’s probably quite obvious that pathogenic microbes are naturally encountered first by the innate immune system nested along mucosal surfaces exposed to the outside environment. The cell-mediated arm of the adaptive branch should be employed secondly upon pathogen invasion, after which the humoral arm should be called into action if need be. Injecting pathogens directly into the bloodstream bypasses this normal sequence and thwarts the appropriate education and maturation of the immune system. Especially for combination vaccines like the MMR shot, a significant suppression of the immune system from virus injection may allow for administered viruses to access tissues throughout the body, particularly the brain [8] [9]. It has been well established that immune system components play an integral role in the growth of the central nervous system, and overstimulation of a developing brain’s microglia through repeated vaccine administrations can bring about CNS damage that includes a loss of dendrites and an obstruction to normal, neural pathway development [10] [11]. The formation of functional and able-bodied memory T-cells after the normal and complete acute clearing of a microbial infection stands in stark contrast to ‘T-cell exhaustion’ from repeated, unnatural injections of the same antigens (which force hurried responses) where T-cells basically give up and allow for pathogen persistence [12]. T-cell exhaustion does not represent boosted immunity toward a pathogen, instead it represents the immune system begging, “please, no more.” More severe T-cell exhaustion is seen with high viral loads or presentations of a large number of epitopes (epitopes are antigen fragments to which antibodies bind), such as those delivered through repeated vaccinations [13]. To mention a few more risks, the simultaneous administration of as few as two adjuvants (like aluminum and mercury) can overcome one’s genetic resistance to autoimmunity, and as expressed by Tsumiyama, Miyazaki, and Shiozawa, “Systemic autoimmunity appears to be the inevitable consequence of over-stimulating the host’s immune ‘system’ by repeated immunization with antigen, to the levels that surpass system’s self-organized criticality” [14] [15]. Additionally, human vaccines have been found to contain such contaminants as lead, bismuth, and titanium, which can contribute to the invoking of adverse events in the short-term, and/or smoldering inflammation that promotes chronic disease in the long-term [16]. Also note that attenuated or “weakened” viruses can and have mutated into more virulent varieties once introduced into the body. Lastly, if vaccines are to be administered to a child, it is my advice that the following recommendations be heeded in order to lessen the risk of adverse events [17]: - Refrain from administering a vaccine while the child is under immunological challenge or is “sick.” - Refrain from administering more than one vaccine at a time. - Preferably separate vaccine administrations by a period of six months or more. - Supplementation with vitamin C, vitamin A, and vitamin D before and after a vaccine administration may help to ameliorate damage and the risk of an adverse event. In closing, I feel a suggestion from Romans 12:2 of the Judeo-Christian Bible is fitting here: “Don’t let the world around you squeeze you into its own mould, but let God re-mould your minds from within…” References:
According to Taoist philosophy, refraining from sexual contact can lead to a dearth of jing (loosely translated as one’s sexual energy), which vivifies and strengthens the body when maintained at a high concentration. Yet excessive ejaculation was seen to cause a “spilling” of one’s jing, depleting and sapping the body. Thus, coitus reservatus was practiced to accumulate sexual energy, retain vigor, and ward off aging [1].
Women can be viewed as wellsprings of nourishing, sexual élan vital which can be shared with their male partner to bolster and harmonize the man’s body. In return, men, personifying the fire element, can offer invigorating dynamism to their female partner. Thus, intercourse stands as a mutually beneficial and constructive vehicle for internal alchemy and unification with the Tao. Outside of Taoist thought, we can describe intimacy as a means for experiencing God through the gateway of unconditional love – with the body, mind, and spirit being enriched or even transformed in the process. Focusing on the corporeal, let’s now examine a collection of avails derivable from loveful mating sourced from the research literature. In both men and women, regular coitus can boost testosterone secretion (though the effect is understandably more pronounced in men) [2]. A higher body mass index has been associated with a lower frequency of penile-vaginal intercourse in men, and a larger waist circumference has been coupled with a smaller history of vaginal orgasm in women [3] [4]. In the same vein, regular visits to horizontal town can assist with weight loss and deflect weight gain [5]. In a sample of over 1,600 college students, Braithwaite, Delevi, and Fincham found that those who were engaged in committed romantic relationships experienced fewer mental health problems and were less likely to be overweight [6]. The deposition of semen within the vaginal canal can result in mood enhancement for her, normalization of the menstrual cycle (to an extent), and deflection of postmenopausal vaginal atrophy [7]. Furthermore, vaginal elasticity, lubrication, and trophism are enhanced by copulation, which may help prevent against issues like chronic cystitis (recurrent bladder infection) [8]. Multiple seminal components can be absorbed into a woman’s bloodstream from semen that has been deposited inside the vagina [9]. In a sample of almost 300 sexually-active college females, fewer depressive symptoms and suicide attempts were found in those who were not employing condoms [10]. Moreover, it is vaginal orgasm by way of penile-vaginal intercourse, as opposed to clitoral orgasm, that is more heavily associated with improved psychological health [11]. There is some evidence linking regular sexual activity with a lower risk for prostate cancer, and it revolves around ejaculation being able to flush xenobiotics and carcinogens from prostatic fluid as well as possibly being able to improve immune surveillance of tumor cells within the prostate gland [12] [13]. In an oft-cited study published in the British Medical Journal, men who had two or more orgasms per week were 50% less likely to die of any cause than men who had fewer orgasms [14]. Engaging in sexual intercourse can better the body’s ability to handle stress, as well as increase the production of brain-derived neurotrophic factor in the hippocampus and improve memory recall [15] [16]. A greater frequency of penile-vaginal intercourse has also been correlated with a lesser incidence of alexithymia (difficulty with emotional awareness and recognition as well as reduced capacity for fantasization) in women [17]. Lastly, here’s a fun fact: a woman’s history of vaginal orgasm can be discerned via her gait and procheilon or upper lip tubercle prominence (though not perfectly of course) [18] [19]. So, as long as your heart can handle the exercise, taking part in passionate lovemaking can do a whole lot for your health! It’s science. References:
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AuthorDenton Coleman is an Exercise Physiologist and Medical Researcher. Archives
October 2023
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